CEO’s competence & expertise
Top Expert in Basic and Clinical Research on Cardiovascular Diseases in Korea
Kiyuk Chang CEO (MD, PhD)
- Professor of Cardiology, Seoul St. Mary's Hospital
- Director of the Cardiovascular and Cerebrovascular Center, Seoul St. Mary's Hospital
- Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea
: Executive Member of the Korean Society of Interventional Cardiology (KSIC) / Executive Member of the Korean Society of Cardiology (KSC) / Chairman of the Consortium Orchestrated Approach for Cardio-cerebro-vascular disease Treatment (COACT)
- Representative Publications
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- Noninvasive Assessment of Myocardial Inflammation by Cardiovascular Magnetic Resonance in a Rat Model of Experimental Autoimmune Myocarditis (2012, Circulation)
- Infarcted Myocardium-Primed Dendritic Cells Improve Remodeling and Cardiac Function After Myocardial Infarction by Modulating the Regulatory T Cell and Macrophage Polarization (2017, Circulation)
- Spatiotemporal dynamics of macrophage heterogeneity and a potential function of Trem2hi macrophages in infarcted hearts (2022, Nat Commun)
- Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial (2021, Lancet)
- Research Achievements
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- (Patent) Tolerogenic dendritic cells for treating myocardial infarction and manufacturing method thereof
- Technology transfer to Pharos Vaccine Co., Ltd. in 2022
- Investigator-initiated Phase 1 clinical trial
